Human phagocytic cell responses toScedosporium prolificans
نویسندگان
چکیده
منابع مشابه
Human phagocytic cell responses to Scedosporium apiospermum (Pseudallescheria boydii): variable susceptibility to oxidative injury.
Scedosporium apiospermum (Pseudallescheria boydii) is an emerging opportunistic filamentous fungus that causes serious infections in both immunocompetent and immunocompromised patients. To gain insight into the immunopathogenesis of infections due to S. apiospermum, the antifungal activities of human polymorphonuclear leukocytes (PMNs), mononuclear leukocytes (MNCs), and monocyte-derived macrop...
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Coccidioides spp. are dimorphic pathogenic fungi whose parasitic forms cause coccidioidomycosis (Valley fever) in mammalian hosts. We use an innovative interdisciplinary approach to analyze one-on-one encounters between human neutrophils and two forms of Coccidioides posadasii. To examine the mechanisms by which the innate immune system coordinates different stages of the host response to funga...
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An experimental skin lesion induced in rabbits by the bite of infected adult Ixodes dammini showed dense dermal interstitial inflammatory cell infiltrates composed of mononuclear cells (histiocytes and lymphocytes) and granulocytes. The prevalence of phagocytic cells in this experimental lesion motivated a study on the interactions of macrophages and neutrophils with Lyme disease spirochetes. I...
متن کاملMolecular and cellular responses of the pathogenic fungus Lomentospora prolificans to the antifungal drug voriconazole
The filamentous fungus Lomentospora (Scedosporium) prolificans is an emerging opportunistic pathogen associated with fatal infections in patients with disturbed immune function. Unfortunately, conventional therapies are hardly of any use against this fungus due to its intrinsic resistance. Therefore, we performed an integrated study of the L. prolificans responses to the first option to treat t...
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ژورنال
عنوان ژورنال: Medical Mycology
سال: 2001
ISSN: 1369-3786,1460-2709
DOI: 10.1080/mmy.39.2.169.175